Atomic structure reveals how cells translate environmental signals

Source: sciencedaily.com
Biotechnology & Biomedical

Culminating a nearly 10 year effort, researchers have determined the atomic resolution structure of a key molecule that translates signals from a cells local environment into a language that the cell can understand and use. The determination of the architecture of the Inositol Tris-Phosphate Receptor (IP3R) had long been considered a major goal in biomedical research because of its strategic role inside cells as a molecular train station for transferring signals that control many cell functions. The structure is expected to contribute to the development of better therapeutic approaches for many diseases.